Federal Bullets is a leisurely paced Monogram crime melodrama with not a few clever plot twists. The FBI, represented by Milburn Stone and William Harrigan, investigates a seemingly respectable charitable organization. In fact, the enterprise is a front for a crime ring, headed by Ma Barker clone Zeffie Tilbury (Trivia note: Ms. Tilbury was totally blind, and had to learn her "blocking" by rote).
| Actor | Role |
|---|---|
 Milburn StoneTommy Thompson, Federal Agent | Tommy Thompson, Federal Agent |
 Zeffie TilburyMrs. Crippen | Mrs. Crippen |
 Terry WalkerMilly | Milly |
 William HarriganFederal Agency Chief | Federal Agency Chief |
 Helen MacKellarMrs. Thompson | Mrs. Thompson |
 Selmer JacksonHarker | Harker |
 Matty Fain'Barber' John | 'Barber' John |
 Betty CompsonSue, Gang Moll | Sue, Gang Moll |
 Warner RichmondHenchman Burke | Henchman Burke |
| LLyle MoraineHenchman Pete | Henchman Pete |