Jay-Z aims to unite the new and older generations of rap fans, while also reflecting on his own infidelity.
| Actor | Role |
|---|---|
 JAŸ-ZSelf | Self |
 BeyoncéSelf | Self |
 Blue Ivy CarterSelf | Self |
 Susan Kelechi WatsonBlue Ivy Carter (adult) | Blue Ivy Carter (adult) |
 Michael B. Jordan2444 Descendant | 2444 Descendant |
 Thandiwe NewtonJoan | Joan |
 Trevante RhodesJoan's lover | Joan's lover |
 Irene BedardMadam President | Madam President |
 Omari HardwickMr. President | Mr. President |
 Jessica ChastainPresidents' interviewer | Presidents' interviewer |
 David Oyelowo2148 Descendant | 2148 Descendant |
 Emayatzy Corinealdi2148 Descendant | 2148 Descendant |
 America FerreraForemother | Foremother |
 Aisha HindsForemother | Foremother |
 Storm Reid2096 Descendant | 2096 Descendant |
 Henry G. Sanders2096 Descendant | 2096 Descendant |
 Brie LarsonForemother | Foremother |
 Constance WuForemother | Foremother |
 Rosario DawsonForemother | Foremother |
 Janet MockForemother | Foremother |
 Mindy KalingForemother | Foremother |
 Rashida JonesForemother | Foremother |
 Niecy NashForemother | Foremother |