After getting fired from his teaching job and dumped by his girlfriend, Jack, a painter, embarks on a soul searching road trip with his dog, Scout. However, bad weather and bumps in the road quickly cause more problems than he can handle. An impulsive decision to take from a bag full of unknown pills leads him on a drug-fueled journey with no destination in sight, and he soon finds himself making both friends and foes along the way.
| Actor | Role |
|---|---|
 Larry HoldenJack Smith | Jack Smith |
| SScoutScout | Scout |
 James HandySign Painter | Sign Painter |
 Shawnee SmithRed Head | Red Head |
 Tony PlanaOfficer Tom | Officer Tom |
 Yolanda SnowballThelma | Thelma |
 Charlotte LewisJill | Jill |
 Doug BudinGeorge | George |
 Daniel EscobarRita | Rita |
 Steve ParkDr. Killdare, D.V.M. | Dr. Killdare, D.V.M. |
 Clint CulpMotel Clerk | Motel Clerk |
 Anne DeSalvoJacquelin | Jacquelin |
 David GrohJack, Sr. | Jack, Sr. |
 Taylor NegronSully | Sully |
 Wesley MannJail Keep | Jail Keep |
 Marty ZagonJudge | Judge |
| NNolan SmithLittle Harry | Little Harry |
 James T. CallahanFather Quinn | Father Quinn |
 Chris SpencerMaurice | Maurice |
| KKate MurtaghLittle Old Lady | Little Old Lady |
| MMike GriefBig Guy | Big Guy |
 Nicholas WorthMel | Mel |
 Paul HewittWorm | Worm |
| EEdward Mark SooraniEddie | Eddie |
| JJoseph Ernest StrongLittle Jack | Little Jack |
| CChris StaceyDishwasher #1 | Dishwasher #1 |
| GGene Jose ReyDishwasher #2 | Dishwasher #2 |
| NNick RobertsonOlder Boy | Older Boy |
| JJ.T. LarsenStudent | Student |
 Johnny KnoxvilleClerk | Clerk |