Horrified by the new girlfriends of their respective sons, three sisters-in-law – Clara, a socialite, Matis, a widowed professional, and Nena, a naive housewife – make an alliance to get rid of their undesirable daughters-in-law.
| Actor | Role |
|---|---|
 Consuelo DuvalClara | Clara |
 Mónica HuarteMatis | Matis |
 Kate del CastilloNena | Nena |
 Michael RondaFernando | Fernando |
 José Eduardo DerbezErnesto | Ernesto |
 Ana Gonzalez BelloElsa | Elsa |
 Ana Sofía GaticaDiana | Diana |
 Fernando MemijeRoberto | Roberto |
 Víctor Huggo MartinArturo | Arturo |
 Sebastián GarciaGuillermo | Guillermo |
 Farah JustinianiFrida | Frida |
 Magali BoysselleAmiga Clara | Amiga Clara |
 Gabriela PlatasAmiga Clara | Amiga Clara |
 Vanessa SabaAmiga Clara | Amiga Clara |
 Martha Claudia MorenoDinorah | Dinorah |
 Gisella AboumradEmpleada Taller | Empleada Taller |
 Artús ChávezPsicólogo | Psicólogo |
| DDavid SalomónGastón | Gastón |
| GGonzalo José GarcíaMarcos | Marcos |
| PPaloma CedeñoJoaquina | Joaquina |
| PPaly DuvalRosario, escort | Rosario, escort |
 Samantha CoronelKarla, escort | Karla, escort |
 Elsie FloresDenisse, escort | Denisse, escort |
| MMicaela ÁvilaActivista | Activista |
 Daniel SosaFotógrafo | Fotógrafo |
| IItzani MárquezPasajera | Pasajera |
 Rocío VerdejoRebeca | Rebeca |
| RRicardo LozanoAbogado | Abogado |