Episodes from an Investigation is an essay/narrative film presented as a series of fragments from the lives of numerous cinephiles and radicals living in 21st Century America. The film cuts between three related narratives: a film collective on a journey to find a mysterious film theorist/filmmaker; a couple whose relationship is falling apart as they each work on pieces concerning the cinematic past and the cinematic present; and two cinematic radicals holed up in an unknown location trying to understand how to revolutionize cinema.
| Actor | Role |
|---|---|
| MMichael BeeAlexander | Alexander |
| GGabriel CastePaul | Paul |
 Josh ChristensenNot listed | Not listed |
| MMick DahlCharles | Charles |
| MMarc DickersonNot listed | Not listed |
| LLaura EdoffAnita | Anita |
| VVictor GennaroArthur | Arthur |
| JJill HackneyNot listed | Not listed |
| AAlex HalpinNot listed | Not listed |
| AAlison HobanVera | Vera |
| EElizabeth LevisonNot listed | Not listed |
| JJake MarianiNot listed | Not listed |
| LLee MinoraAnn | Ann |
| PPhoebe SchaubAgnes | Agnes |
| JJonathan SeidmanNot listed | Not listed |