Movie star Vincent Chase, together with his boys, Eric, Turtle and Johnny, are back…and back in business with super agent-turned-studio head Ari Gold. Some of their ambitions have changed, but the bond between them remains strong as they navigate the capricious and often cutthroat world of Hollywood.
| Actor | Role |
|---|---|
 Kevin ConnollyEric Murphy | Eric Murphy |
 Adrian GrenierVincent 'Vince' Chase | Vincent 'Vince' Chase |
 Kevin DillonJohnny 'Drama' Chase | Johnny 'Drama' Chase |
 Jerry FerraraTurtle | Turtle |
 Jeremy PivenAri Gold | Ari Gold |
 Emmanuelle ChriquiSloane | Sloane |
 Perrey ReevesMrs. Ari | Mrs. Ari |
 Rex LeeLloyd | Lloyd |
 Debi MazarShauna | Shauna |
 Rhys CoiroBilly Walsh | Billy Walsh |
 Constance ZimmerDana Gordon | Dana Gordon |
 Haley Joel OsmentTravis McCredle | Travis McCredle |
 Ronda RouseyRonda Rousey | Ronda Rousey |
 Kid CudiAllen | Allen |
 Alan DaleJohn Ellis | John Ellis |
 Emily RatajkowskiEmily Ratajkowski | Emily Ratajkowski |
 Billy Bob ThorntonLarsen McCredle | Larsen McCredle |
 Nina AgdalBridgite | Bridgite |
| LLucas EllinJonah | Jonah |
 Piers MorganPiers Morgan | Piers Morgan |
| RRockyArnold | Arnold |
 Mark CubanMark Cuban | Mark Cuban |
 Sabina GadeckiMelanie | Melanie |
 Thierry HenryThierry Henry | Thierry Henry |
| MMax EllinThierry's Dog | Thierry's Dog |
 Jennie KwanOB/GYN Nurse | OB/GYN Nurse |
 T.I.T.I. | T.I. |
| TTiny HarrisTameka Harris | Tameka Harris |
 SaigonSaigon | Saigon |
 Rob GronkowskiRob Gronkowski | Rob Gronkowski |