The fight for Sinaloa will lead the two most important cartels in the country to betray and deceive whoever is necessary to seize it, be it the police themselves or federal agencies.
| Actor | Role |
|---|---|
 Óscar LópezEl Barbas | El Barbas |
| FFabián LópezÁlvaro | Álvaro |
 Alan CiangherottiManuel Torres | Manuel Torres |
| AAlex SirventJoaquín | Joaquín |
 John SolisIsrael | Israel |
 Miguel Ángel SaldañaCaimán | Caimán |
| EEva MartínezSandra | Sandra |
| AAndrea ZúñigaJazmín | Jazmín |
| VViviana PáezPilar | Pilar |