Between performances of his magic show, Fu-Manchu must solve the mystery of a haunted house, where several séances are held and numerous supernatural phenomena take place.
| Actor | Role |
|---|---|
 David T. BambergFu Manchu | Fu Manchu |
 Manuel MedelSatanás | Satanás |
 Josefina EscobedoMadame Dubois (médium) | Madame Dubois (médium) |
 Miguel Ángel Ferriz Sr.Licenciado | Licenciado |
 Narciso BusquetsJuanito | Juanito |
| MMimí DerbaSeñora Guzmán | Señora Guzmán |
 José PidalDoctor Adalberto Zuno, espiritista | Doctor Adalberto Zuno, espiritista |
 Ángel T. SalaTeniente Palomino | Teniente Palomino |
| AAgustín SenSr. Fernández, empresario | Sr. Fernández, empresario |
 Julio AhuetLucas, el chofer | Lucas, el chofer |
| CCuquita EscobarAsistente Fu Manchu | Asistente Fu Manchu |
 Hernán VeraOperador cabina sitio de taxis (uncredited) | Operador cabina sitio de taxis (uncredited) |