ECW One Night Stand (2006) was a PPV produced by World Wrestling Entertainment (WWE). It was held on June 11, 2006 at the Hammerstein Ballroom in New York, New York. The main event was John Cena versus Rob Van Dam for the WWE Championship. The predominant match on the undercard was Rey Mysterio versus Sabu for the World Heavyweight Championship. Another match on the undercard was Edge, Mick Foley, and Lita versus Terry Funk, Tommy Dreamer and Beulah McGillicutty in a Hardcore Intergender match.
| Actor | Role |
|---|---|
 John CenaSelf | Self |
 Rob SzatkowskiRob Van Dam | Rob Van Dam |
 Óscar Gutiérrez RubioRey Mysterio | Rey Mysterio |
 Terry BrunkSabu | Sabu |
 Terry FunkSelf | Self |
 Tom LaughlinTommy Dreamer | Tommy Dreamer |
 Trisa LaughlinBeulah McGillicutty | Beulah McGillicutty |
 Mick FoleySelf | Self |
 Adam CopelandEdge | Edge |
 Amy DumasLita | Lita |
 Balls MahoneySelf | Self |
 Kurt AngleSelf | Self |
 Randy OrtonSelf | Self |
 Peter SenerchiaTazz | Tazz |
 Jerry LawlerSelf | Self |
 Francisco RuedaSuper Crazy | Super Crazy |
 James MaritatoLittle Guido | Little Guido |
 Charles SpencerTony Mamaluke | Tony Mamaluke |
 Mike IorioBig Guido | Big Guido |
 Paul HeymanSelf | Self |
 John LayfieldSelf | Self |
 Jim FullingtonThe Sandman | The Sandman |
 Nick DinsmoreEugene | Eugene |
 Stephanie FinochioTrinity | Trinity |