A psychiatrist struggles to aid her stranded family and patients while grappling with her own mental state.
| Actor | Role |
|---|---|
 Tara ReidDr. Quarantine | Dr. Quarantine |
| LLaurel NailElizabeth | Elizabeth |
| AAfi AyannaHarper's Mom | Harper's Mom |
 Fabian ArnoldFinn | Finn |
| KKerry BazarovaJackie's Mom (Younger) | Jackie's Mom (Younger) |
| EEthan Reese JonesEmergency Dispatcher | Emergency Dispatcher |
| MMichelle YinViolinist Michelle | Violinist Michelle |
| BBrindisi CapriHarper | Harper |
 Philip V. BruennOfficer Moon | Officer Moon |
| JJared VineyardOfficer Eric Scott-Douglas | Officer Eric Scott-Douglas |
| SScotch HopkinsNeighbor | Neighbor |
| NNaomi AyendeVeronica | Veronica |
| HHunter LintonOfficer Landau | Officer Landau |
 Serena SalieriCoughing Woman in Laundry Room | Coughing Woman in Laundry Room |
 Calique PérezNolan | Nolan |
| SSeth PalmquistAiden | Aiden |
| EErik Handsome SmallsBob | Bob |