Dr. Gillespie supports Kildare's crusade against their hospital's deal with a rival hospital.
| Actor | Role |
|---|---|
 Lew AyresDr. James Kildare | Dr. James Kildare |
 Lionel BarrymoreDr. Leonard Gillespie | Dr. Leonard Gillespie |
 Ann AyarsCynthia 'Cookie' Charles | Cynthia 'Cookie' Charles |
 Robert SterlingDr. Donald 'Don' Winthrop | Dr. Donald 'Don' Winthrop |
 Jean RogersMiss Annabelle Kirke | Miss Annabelle Kirke |
 Alma KrugerMolly Byrd | Molly Byrd |
 Walter KingsfordDr. Walter Carew | Dr. Walter Carew |
 Nell CraigNurse Parker | Nurse Parker |
 Edward GarganWillie Brooks | Willie Brooks |
 Marie BlakeSally | Sally |
 Frank OrthMike Ryan | Mike Ryan |
 George H. ReedConover (as George H. Reed) | Conover (as George H. Reed) |
 Barry NelsonSamuel Z. Cutter | Samuel Z. Cutter |
 Eddie AcuffClifford Genet | Clifford Genet |
| GGus SchillingLeo Cobb | Leo Cobb |
 Stuart CrawfordArnold Spencer | Arnold Spencer |
 William BakewellMr. Hubbell | Mr. Hubbell |
 Charlotte WyntersMrs. Hubbell | Mrs. Hubbell |