Recluse Dr. Nina Jekyll befriends with her newly hired help, Rob. They must work together to prevent Hyde from destroying her life.
| Actor | Role |
|---|---|
 Suzy Eddie IzzardDr. Nina Jekyll / Rachel Hyde | Dr. Nina Jekyll / Rachel Hyde |
 Scott ChambersRob | Rob |
 Lindsay DuncanSandra Poole | Sandra Poole |
 Robyn CaraMaeve | Maeve |
 Jonathan HydeHenry Jekyll | Henry Jekyll |
 Morgan WatkinsEwan | Ewan |
 Simon CallowJournalist | Journalist |
 Tony JayawardenaMalcolm | Malcolm |
| IIsabella InchbaldNina's Mother | Nina's Mother |