 Morgan ConwayDick Tracy | Dick Tracy |
 Anne JeffreysTess Trueheart / Blythe Belmonte | Tess Trueheart / Blythe Belmonte |
 Lyle LatellPat Patton | Pat Patton |
 Rita CordayMona Clyde, Sparkle's Secretary | Mona Clyde, Sparkle's Secretary |
 Ian KeithVitamin Flintheart | Vitamin Flintheart |
 Dick WesselHarry 'Cueball' Lake | Harry 'Cueball' Lake |
 Douglas WaltonPercival Priceless, Antique Store Owner | Percival Priceless, Antique Store Owner |
 Esther HowardFilthy Flora, Dripping Dagger Proprietor | Filthy Flora, Dripping Dagger Proprietor |
 Joseph CrehanChief Brandon | Chief Brandon |
 Byron FoulgerSimon Little, Sparkle's Diamond Cutter | Simon Little, Sparkle's Diamond Cutter |
| JJimmy CraneJunior | Junior |
| JJimmy Clemons Jr.Butch | Butch |
 Milton ParsonsHigby | Higby |
 Skelton KnaggsRudolph | Rudolph |
 Trevor BardetteAbbott | Abbott |
 Harry CheshireJules Sparkle | Jules Sparkle |
 Fred AldrichShip Officer (uncredited) | Ship Officer (uncredited) |
 George BarrowsCrewman (uncredited) | Crewman (uncredited) |
 Eddie BordenDrunk (uncredited) | Drunk (uncredited) |
 Robert BraySteve (uncredited) | Steve (uncredited) |
 Jack CheathamCop (uncredited) | Cop (uncredited) |
| Harry CheshireJules Sparkle (uncredited) | Jules Sparkle (uncredited) |
 Ralph DunnPoliceman (uncredited) | Policeman (uncredited) |
| LLee FrederickPurser (uncredited) | Purser (uncredited) |
| RRaoul FreemanPoliceman (uncredited) | Policeman (uncredited) |
 Dorothy GrangerLeeds (uncredited) | Leeds (uncredited) |
 Kit GuardBar Customer (uncredited) | Bar Customer (uncredited) |
| PPerc LaundersTelephone Operator (uncredited) | Telephone Operator (uncredited) |
 Robert MilaschBar Customer (uncredited) | Bar Customer (uncredited) |
 Frank MillsDrunk (uncredited) | Drunk (uncredited) |
