In 1950s New York City, a bad and bloody gang war is about to erupt on the dysfunctional streets of Brooklyn between the Deuces and the vicious Vipers.
| Actor | Role |
|---|---|
 Stephen DorffLeon | Leon |
 Brad RenfroBobby | Bobby |
 Fairuza BalkAnnie | Annie |
 Norman ReedusMarco | Marco |
 Max PerlichFreddie | Freddie |
 Drea de MatteoBetsy | Betsy |
 Vincent PastoreFather Aldo | Father Aldo |
 Frankie MunizScooch | Scooch |
 Balthazar GettyJimmy Pockets | Jimmy Pockets |
 Nancy CassaroEsther | Esther |
 Matt DillonFritzy | Fritzy |
 Debbie HarryWendy | Wendy |
 James FrancoTino | Tino |
 Joshua LeonardPunchy | Punchy |
 Ava Lee ScottBrenda | Brenda |
| DDanny CistoneLittle Jack | Little Jack |
 Louis LombardiPhilly Babe | Philly Babe |
 Johnny KnoxvilleVinnie Fish | Vinnie Fish |
 Mel RodriguezBig Dom | Big Dom |
 Robert MirandaGino | Gino |
| SShamus MurphyPatty Cugire | Patty Cugire |
 Ronnie MarmoMoof | Moof |
 Paul SampsonJoey Pants | Joey Pants |
 Maurice CompteMaurice | Maurice |
| GGeorge GeorgiadisWillie | Willie |
 Jackie TohnMary Ann | Mary Ann |
 George PalermoStevie Olives | Stevie Olives |
 Steve PicerniJerry | Jerry |
| MMarc Alexander SferrazzaYoung Boy at Pool | Young Boy at Pool |
 Blake BashoffAllie Boy | Allie Boy |