Life for teenage versions of Wonder Woman, Supergirl and Batgirl is complicated as they try to balance their schoolwork with secret identities and fighting crime.
| Actor | Role |
|---|---|
 Tara StrongBatgirl / Harleen Quinzel (voice) | Batgirl / Harleen Quinzel (voice) |
 Nicole SullivanSupergirl (voice) | Supergirl (voice) |
 Grey DeLisleWonder Woman (voice) | Wonder Woman (voice) |
 Myrna VelascoJessica Cruz (voice) | Jessica Cruz (voice) |
 Kimberly BrooksBumblebee / Eliza Danvers / Alexandra (voice) | Bumblebee / Eliza Danvers / Alexandra (voice) |
 Kari WahlgrenZatanna / Lillian Luthor / News Anchor (voice) | Zatanna / Lillian Luthor / News Anchor (voice) |
 Keith FergusonJeremiah Danvers / Demo-Bot Foreman (voice) | Jeremiah Danvers / Demo-Bot Foreman (voice) |
 Cassandra Lee MorrisLena Luthor (voice) | Lena Luthor (voice) |
 Will FriedleLex Luthor / Truant Officer / Aiden (voice) | Lex Luthor / Truant Officer / Aiden (voice) |
 Phil LaMarrMr. Zatara / Barry Allen (voice) | Mr. Zatara / Barry Allen (voice) |
 Jason SpisakHal Jordan (voice) | Hal Jordan (voice) |
 Cree SummerHippolyta (voice) | Hippolyta (voice) |
 Fred TatascioreCommissioner Gordon / Mr. Chapin (voice) | Commissioner Gordon / Mr. Chapin (voice) |