Darkman, needing money to continue his experiments on synthetic skin, steals a crate of cash from drug lord Peter Rooker...
| Actor | Role |
|---|---|
 Jeff FaheyPeter Rooker | Peter Rooker |
 Arnold VoslooPeyton Westlake / Darkman | Peyton Westlake / Darkman |
 Darlanne FluegelDr. Bridget Thorne | Dr. Bridget Thorne |
 Roxann DawsonAngela Rooker | Angela Rooker |
 Nigel BennettNico | Nico |
| AAlicia PanettaJenny Rooker | Jenny Rooker |
 Ronn SarosiakMack | Mack |
| PPeter GrahamJoey | Joey |
 Shawn DoyleAdam | Adam |
 Vieslav KrystyanIvan | Ivan |
| CChris AdamsWhit | Whit |
 Rick ParkerE.K. | E.K. |
 Joel BissonnetteMayo | Mayo |
 John NovakRyan Mitchell | Ryan Mitchell |
 Christopher BondyGibson (as Chris Bondy) | Gibson (as Chris Bondy) |
 Von FloresJohnny Lee | Johnny Lee |
| EEric HolloPaul Raney | Paul Raney |
| GGino GiacominiBeast | Beast |
| LLance PatonNarrator | Narrator |
| SSuzanne PrimeauMother | Mother |
| RRobert WindsorUncle Owen | Uncle Owen |
| RRene Beau Dean HuardMitchell Supporter | Mitchell Supporter |
| LLorne CossetteDr. Leonard | Dr. Leonard |
 Diana PlattsReporter #1 | Reporter #1 |
 Joanne ReeceReporter #2 | Reporter #2 |
| WWalker BooneSergeant Troy | Sergeant Troy |
 Michelle CollinsNurse | Nurse |
 Brian PaulAngry Guest | Angry Guest |
| DDenise BaillargeonFemale Guest | Female Guest |