Darkman and Durant return and they hate each other as much as ever. This time, Durant has plans to take over the city's drug trade using high-tech weaponry. Darkman must step in and try to stop Durant once and for all.
| Actor | Role |
|---|---|
 Larry DrakeRobert G. Durant | Robert G. Durant |
 Arnold VoslooPeyton Westlake / Darkman | Peyton Westlake / Darkman |
 Kim DelaneyJill Randall | Jill Randall |
 Renée O'ConnorLaurie Brinkman | Laurie Brinkman |
 Lawrence DaneDr. Alfred Hathaway | Dr. Alfred Hathaway |
 Jesse CollinsDr. David Brinkman | Dr. David Brinkman |
 David FerryEddie | Eddie |
 Rod WilsonIvan Druganov | Ivan Druganov |
 Jack LangedijkRollo Latham | Rollo Latham |
 Sten EirikWhitey | Whitey |
 Steve MousseauRoy | Roy |
 James MillingtonMr. Perkins | Mr. Perkins |
 Phillip JarrettDan | Dan |
 Kevin RushtonSkinhead | Skinhead |
 Graham RowatProducer Bob | Producer Bob |
 Chris GillettBob's Boss | Bob's Boss |
| DDavid ClementDet. Stringer | Det. Stringer |
| CCatherine SwingBonnie Cisco | Bonnie Cisco |
 Anne Marie DeLuiseReceptionist | Receptionist |
| AAdam BrambleDoctor | Doctor |
| HHarry SpiegelCabbie | Cabbie |
| CCandice BeaulieuLittle Girl | Little Girl |
| DDonna MullinMiss S&M | Miss S&M |