Confined to an asylum for the criminally insane for the past four years, Nica is wrongly convinced that she, not Chucky, murdered her entire family... until a string of grisly deaths occur after her psychiatrist introduces a new group therapy tool -- a "Good Guy" doll.
| Actor | Role |
|---|---|
 Fiona DourifNica | Nica |
 Brad DourifChucky (voice) | Chucky (voice) |
 Alex VincentAndy | Andy |
 Jennifer TillyTiffany | Tiffany |
 Michael TherriaultDr. Foley | Dr. Foley |
 Adam HurtigMichael | Michael |
 Elisabeth RosenMadeline | Madeline |
 Zak SantiagoNurse Carlos | Nurse Carlos |
 Ali TatarynNurse Ashley | Nurse Ashley |
 Grace Lynn KungClaire | Claire |
 Marina Stephenson KerrAngela | Angela |
 Allison Dawn DoironRachel | Rachel |
 Summer H. HowellAlice | Alice |
 Christine EliseKyle | Kyle |
 Tom AnnikoChaplain | Chaplain |
| DDarren WallAsylum Guard | Asylum Guard |
 Dan De JaegerOrderly #1 | Orderly #1 |
 Matthew StefansonOrderly #2 | Orderly #2 |
 Dennis ScullardAsylum Patient (uncredited) | Asylum Patient (uncredited) |
| AAidan RitchieAsylum Patient (uncredited) | Asylum Patient (uncredited) |
 Linden PorcoBody (uncredited) | Body (uncredited) |
 Lorrie PapadopoulosAsylum Patient (uncredited) | Asylum Patient (uncredited) |
| PPaolo BryantOrderly (uncredited) | Orderly (uncredited) |