Renfrew of the Mounties hunts brother-and-sister gold hijackers.
| Actor | Role |
|---|---|
 James NewillRCMP Sgt. Renfrew | RCMP Sgt. Renfrew |
 Warren HullConstable Kelly | Constable Kelly |
 Jean CarmenAnn 'Angel' Chambers | Ann 'Angel' Chambers |
 Milburn StoneDelos Harrington | Delos Harrington |
 Walter ByronMcClusky | McClusky |
 Stanley BlystoneJim LaMont | Jim LaMont |
 Robert FrazerDoctor Smith | Doctor Smith |
 Joseph W. GirardSteamship Captain | Steamship Captain |
 Dave O'BrienFred Chambers | Fred Chambers |
| EEarl DouglasSlant Eye | Slant Eye |
 Ted AdamsEskimo Pete | Eskimo Pete |
 Roy BarcroftHenchman Green | Henchman Green |
 Iron Eyes CodyIndian Joe - Harrington's Henchman | Indian Joe - Harrington's Henchman |
 Horace MurphyBoat Passenger | Boat Passenger |
 Harry SemelsMan Who Reports Gunfight | Man Who Reports Gunfight |
| WWally WestShip's Officer | Ship's Officer |