A pair of second grade girls, Parker and Maggie, are playing at a playground when Maggie touches a boy's hand, unaware that she just contracted the cooties. She and Parker must work together to find the cure before it's too late.
| Actor | Role |
|---|---|
 Kinley MoodyParker | Parker |
| EEloise PeltekianMaggie | Maggie |
| YYanick WelihozkiyOllie/Paulie | Ollie/Paulie |
| AAddison QuamMaggie/Man Monster | Maggie/Man Monster |