It's Charlie Sheen's turn to step in to the celebrity hot seat for the latest installment of The Comedy Central Roast.
| Actor | Role |
|---|---|
 Seth MacFarlaneSelf - Roastmaster | Self - Roastmaster |
 Charlie SheenSelf - Roastee | Self - Roastee |
 Kate WalshSelf - Roaster | Self - Roaster |
 William ShatnerSelf - Roaster | Self - Roaster |
 Jon LovitzSelf - Roaster | Self - Roaster |
 Amy SchumerSelf - Roaster | Self - Roaster |
 Mike TysonSelf - Roaster | Self - Roaster |
 Steve-OSelf - Roaster | Self - Roaster |
 Jeff RossSelf - Roaster | Self - Roaster |
 SlashSelf - Guitar Player | Self - Guitar Player |
 Anthony JeselnikSelf - Roaster | Self - Roaster |
 Patrice O'NealSelf | Self |