Jim Matthews, a PR exec for a genetic design firm, is sleeping with Jenny Dole, a secretary. When Meredith Weaver (Jim's wife and a genetic designer with the firm) finds out about the affair, she doses him with an experimental serum, causing his limbs to separate from his body and take on lives of their own.
| Actor | Role |
|---|---|
| JJoan DincoJenny Dole | Jenny Dole |
| DDavid RommelJim Matthews | Jim Matthews |
| AAnna ZizzoMeredith Weaver | Meredith Weaver |
| SSusan L. CaneSuzanne Dole | Suzanne Dole |
| CClayton SimchickPrivate Investigator | Private Investigator |
| TTammy AndersenKris | Kris |
| RRaymond BradfordOperator (voice) | Operator (voice) |
| NNancy BrownColleen | Colleen |
| SSteven F.L. DompkeSecurity Guard | Security Guard |
| TTom FuginaDr. Collins | Dr. Collins |
| GGregor HernandezMugger | Mugger |
| CCarri KrehlSharon | Sharon |
| JJ. Elizabeth MarhalMary | Mary |
| YYeng MonroeRenee | Renee |
| BBill OlsenKelly | Kelly |
| TThomas BernaBum #1 | Bum #1 |
| RRobert Paul UlrichBum #2 | Bum #2 |
| FFelix BofilWaiter | Waiter |
| JJoanna Berman(voice) | (voice) |
| GGail Berna(voice) | (voice) |
| JJoe Idej(voice) | (voice) |
| HHope Januchowski(voice) | (voice) |
| JJennifer Schweiger(voice) | (voice) |
| CCrystal Simchick(voice) | (voice) |
| JJames Tiberius(voice) | (voice) |