Colin Jost and Michael Che, co-anchors of the wildly popular Saturday Night Live Weekend Update sketch, host a 60-minute live stand-up special featuring a mix of up-and-coming and established comics hand-selected and curated by the pair.
| Actor | Role |
|---|---|
 Colin JostSelf - Host | Self - Host |
 Michael CheSelf - Host | Self - Host |
 Tracy MorganNot listed | Not listed |
 Sarah ShermanSelf - Guest | Self - Guest |
 Alex EnglishSelf - Performer | Self - Performer |
 Aida RodríguezSelf - Performer | Self - Performer |
 Sal VulcanoSelf - Guest | Self - Guest |
 Aminah ImaniSelf - Performer | Self - Performer |
 Karlous MillerSelf - Performer | Self - Performer |
 Mike BirbigliaSelf - Performer | Self - Performer |