Chauvinistic businessman Leo Blockman picks up a woman who shoots him, causing him to fall into a river and inexplicably emerge as a woman. Renaming herself Cleo Clock, her female personality gradually begins to take over, and she's forced to navigate a sexist world while attempting to find a way to transform back into a man.
| Actor | Role |
|---|---|
 Veronica HartCleo Clock | Cleo Clock |
 Scott BakerLeo Blockman | Leo Blockman |
 Kevin ThomsenBob Miller | Bob Miller |
| AAlan NaggarMarvin Blockman | Marvin Blockman |
 Ginger Lynn AllenKaren | Karen |
| FFrank StewartBenedict | Benedict |
 Ruth CollinsSally | Sally |
 Jennifer DeloraBernice | Bernice |
| JJoe GiardinaEarl | Earl |
 Paul BorgheseFred | Fred |
| RRichard MarisDave | Dave |
 Philip CampanaroAl | Al |
 Kimberly TaylorStore Clerk | Store Clerk |
| AAudrey QuarlesBank Teller | Bank Teller |
| RRichard GuideKenny | Kenny |
| CCarol FordBig Big Woman | Big Big Woman |
 Katherine OlsenRuth Blockman | Ruth Blockman |
| CChristopher HamiltonEric Blockman | Eric Blockman |
| RRobinette LloydWaitress | Waitress |
| DDavid AnthonyHard Hat 1 | Hard Hat 1 |
| MMichael MonaghanHard Hat 2 | Hard Hat 2 |
 Daniel ChapmanApe | Ape |
| CCatherine SchullerFemale Mechanic | Female Mechanic |
| HHaskell PhillipsBusinessman | Businessman |
| LLoretta PalmaKitty Miller | Kitty Miller |
 Debbie RochonReporter | Reporter |
| KKurt SinclairRuth's Boyfriend | Ruth's Boyfriend |
 Allen Lewis RickmanMinister | Minister |
 Monique GabrielleBimbo (uncredited) | Bimbo (uncredited) |