Christopher Columbus's crazy idea of traveling to India can only be realized because the Spanish treasury is empty and Queen Isabella, who rules the country, is charmed by the charming, profit-seeking son of a poor weaver. With the ulterior motive of becoming the ruler of new lands and at the same time being able to polish up the ailing finances a little, Isabella commissions the navigator Columbus to set sail for the Spanish crown.
| Actor | Role |
|---|---|
 Karl Michael VoglerChristoph Kolumbus | Christoph Kolumbus |
 Udo VioffAmerigo Vespucci | Amerigo Vespucci |
 Joseph OffenbachKanzler Santangel | Kanzler Santangel |
 Klaus SchwarzkopfJosé Vendrino | José Vendrino |
 Maria SebaldtMarchesa Beatrice de Moya | Marchesa Beatrice de Moya |
 Margot TroogerKönigin Isabella | Königin Isabella |
 Theo LingenKönig Ferdinand | König Ferdinand |
 Harry WüstenhagenQuintanilla | Quintanilla |
| WWalter HoorPepi damals | Pepi damals |
 Hans ClarinPepi heute | Pepi heute |
 Hannelore ElsnerAnacoana | Anacoana |
 Edgar HoppeDiego | Diego |
 Gernot DudaRodrigo | Rodrigo |
| MMichael HabeckDicky | Dicky |
 Henning SchlüterKoch | Koch |
 Benno HoffmannMedizinmann | Medizinmann |
| HHerbert WeißbachSteuerbeamter | Steuerbeamter |
 Friedrich MaurerErzbischof | Erzbischof |