 Pat O'BrienDave Logan | Dave Logan |
 Beverly RobertsJean Logan | Jean Logan |
 Ross AlexanderTom Collins | Tom Collins |
 Humphrey BogartHap Stuart | Hap Stuart |
 Marie WilsonSunny Avery | Sunny Avery |
 Joseph CrehanJim Horn | Jim Horn |
 Joe KingMr. Pierson | Mr. Pierson |
 Addison RichardsMr. B.C. Hill | Mr. B.C. Hill |
| RRuth RobinsonMother Brunn | Mother Brunn |
 Henry B. WalthallDad Brunn | Dad Brunn |
 Carlyle Moore Jr.Radio Operator on Clipper | Radio Operator on Clipper |
| LLyle MoraineCo-Pilot on Clipper | Co-Pilot on Clipper |
 Dennis MooreEngineer on Clipper | Engineer on Clipper |
 Wayne MorrisNavigator on Clipper | Navigator on Clipper |
 Alexander CrossBill Andrews | Bill Andrews |
 William WrightPilot | Pilot |
 Kenneth HarlanDepartment of Commerce Inspector | Department of Commerce Inspector |
 Anne NagelSecretary | Secretary |
 Marjorie WeaverSecretary | Secretary |
 Milburn StoneRadio Operator | Radio Operator |
| OOwen KingRadio Operator | Radio Operator |
 Irving BaconCharlie - the Janitor (uncredited) | Charlie - the Janitor (uncredited) |
 George BerangerWaiter (uncredited) | Waiter (uncredited) |
| JJohn ButlerSecond Commerce Inspector (uncredited) | Second Commerce Inspector (uncredited) |
 Glen CavenderPan American Union Waiter (uncredited) | Pan American Union Waiter (uncredited) |
| JJoe CunninghamJack - a Weatherman (uncredited) | Jack - a Weatherman (uncredited) |
 Hal K. DawsonAirplane Designer (uncredited) | Airplane Designer (uncredited) |
 Ralph DunnPlane Announcer at Miami Airport (uncredited) | Plane Announcer at Miami Airport (uncredited) |
 Bill ElliottPilot (uncredited) | Pilot (uncredited) |
 Frank FaylenWeatherman (uncredited) | Weatherman (uncredited) |
