When James and Janet Marston find, after the birth of their second son, that they can have no more they decide to adopt. The result is a huge family of up to sixty children of all nationalities, races and creeds and some with physical and mental disabilities. Their happiness, however, is not to continue without problems...
| Actor | Role |
|---|---|
 Stephanie ZimbalistJanet Marston | Janet Marston |
 James ReadJames Marston | James Marston |
 Diane LaddMrs. Heflin | Mrs. Heflin |
 Ed Begley Jr.Jake | Jake |
 Anne HaneyJudge Gelson | Judge Gelson |
 Royce D. ApplegateShawn | Shawn |
 Sandy KenyonNot listed | Not listed |
 Richard LinebackNot listed | Not listed |
 Joe NesnowNot listed | Not listed |
 Olivia BurnetteEllie | Ellie |
| JJoel GravesNot listed | Not listed |
| JJohnny Jason GraveNot listed | Not listed |
| VVaughn Tyree JelksRicky | Ricky |
 Aaron LohrNot listed | Not listed |
| NNellie BellflowerMrs. Polone | Mrs. Polone |
| DDaniel Bryan CartwellMr. Marston | Mr. Marston |
| JJudy Jean BernsMrs. Duncan | Mrs. Duncan |
| MMary-Margaret LewisMiss Jorgenson | Miss Jorgenson |
 Julie MannixNurse | Nurse |
 Lou LiberatoreDoctor | Doctor |
| TTerry BurnsDr. Anderson | Dr. Anderson |
| MMort SertnerBailiff | Bailiff |
| PPeter JollyP.E. Instructor | P.E. Instructor |
| WWeldon BleilerMinister | Minister |
| CConnie LewSoo Ling | Soo Ling |
| MMindy ZazanisGinny | Ginny |
| DDavid FeitBobby | Bobby |
| LLael BarronesLael | Lael |
| JJennifer EstlowJennifer | Jennifer |
| CChristopher PetersChristopher | Christopher |