 Yahya Abdul-Mateen IIWayne Strider | Wayne Strider |
 Mark WahlbergGregory Scarpa | Gregory Scarpa |
 Nicole BeharieAllison Strider | Allison Strider |
 Josh LucasSpecial Agent Everett Rhodes | Special Agent Everett Rhodes |
 David StrathairnSpecial Agent Roy K. Moore | Special Agent Roy K. Moore |
 Giancarlo EspositoVernon Dahmer | Vernon Dahmer |
 Ethan EmbrySam Bowers | Sam Bowers |
 LisaGay HamiltonMs. Rebecca Brewer | Ms. Rebecca Brewer |
 LaChanzeHattie Dahmer | Hattie Dahmer |
| BBiko Eisen-MartinSpecial Agent Archie Crawford | Special Agent Archie Crawford |
 Will BrittainBilly Roy Pitts | Billy Roy Pitts |
| DDeVere JehlEdgar Ray Killen | Edgar Ray Killen |
 Jody ThompsonLawrence Byrd | Lawrence Byrd |
 Zach LaneHoward Styles | Howard Styles |
 Lee PerkinsSheriff Mitchell | Sheriff Mitchell |
| JJohn C. MartinState Trooper Jones | State Trooper Jones |
 Daniel AnnoneSpecial Agent Anthony Villano | Special Agent Anthony Villano |
 Alanna MastersonConnie Scarpa | Connie Scarpa |
| MMike HickmanBobby Gilmer | Bobby Gilmer |
 Jobie JamesPhotographer | Photographer |
 Scott KasicsPhotographer | Photographer |
| EElizabeth GibbsLinda Schiro | Linda Schiro |
 Asher AlexanderJoey Scarpa | Joey Scarpa |
 Cam HealyGreg Scarpa Jr. | Greg Scarpa Jr. |
 Adam VernierDeputy | Deputy |
| TTodd WarrenFBI Driver | FBI Driver |
| JJude ZarzaurTommy Scarpa | Tommy Scarpa |
| TTiffany GreeneDiner Waitress | Diner Waitress |
 Nicholas LoganJedidiah | Jedidiah |
| NNova Valentina BiggersBettie Dahmer | Bettie Dahmer |
