Depicts Hamka's childhood in Maninjau, West Sumatra, where he showed a great interest in tradition and literature, despite neglecting his education at the pesantren and often clashing with his father. After his mother divorced his father, Hamka went to Mecca to learn about organization, the hajj manasik system, and to pursue his life's greatest mission, building Islam in Indonesia. However, Hamka still struggled with his father and met Siti Raham, an extraordinary woman who became his greatest inspiration in life.
| Actor | Role |
|---|---|
 Vino G. BastianBuya Hamka | Buya Hamka |
 Laudya Cynthia BellaSiti Raham | Siti Raham |
 Donny DamaraHaji Rasul | Haji Rasul |
 Mathias MuchusSutan Mansur | Sutan Mansur |
 Teuku Rifnu WikanaKariman Amin | Kariman Amin |
 Desy RatnasariUmmi Safiah | Ummi Safiah |
 Ayu LaksmiAndung | Andung |
 Marthino LioAmir | Amir |
 AnjasmaraSoekarno | Soekarno |
 Reza RahadianH.O.S. Tjokroaminoto | H.O.S. Tjokroaminoto |
 Verdi SolaimanAbdul Karim/ Oei Tjeng Hien | Abdul Karim/ Oei Tjeng Hien |
 Rey BongHamka (young) | Hamka (young) |
 Bima AzrielRusydi (young) | Rusydi (young) |
| IIzzati KhansaSiti Raham (young) | Siti Raham (young) |
 Zayyan SakhaZaki (young) | Zaki (young) |