 Richard GereOff. Eddie Dugan | Off. Eddie Dugan |
 Don CheadleDet. Clarence 'Tango' Butler | Det. Clarence 'Tango' Butler |
 Ethan HawkeDet. Sal Procida | Det. Sal Procida |
 Wesley SnipesCasanova 'Caz' Phillips | Casanova 'Caz' Phillips |
 Vincent D'OnofrioBobby 'Carlo' Powers | Bobby 'Carlo' Powers |
 Ellen BarkinAgent Smith | Agent Smith |
 Michael Kenneth WilliamsRed | Red |
 Shannon KaneChantel | Chantel |
 Brían F. O'ByrneDet. Ronny Rosario | Det. Ronny Rosario |
 Will PattonLt. Bill Hobarts | Lt. Bill Hobarts |
 Lili TaylorAngela Procida | Angela Procida |
 Wass StevensDet. Patrick Leary | Det. Patrick Leary |
 Armando RiescoDet. George Montress | Det. George Montress |
 Wade Allain-MarcusC-Rayz | C-Rayz |
 Logan Marshall-GreenMelvin Panton | Melvin Panton |
 Jesse WilliamsE. Quinlan | E. Quinlan |
 Hassan JohnsonBeamer | Beamer |
 Jas AndersonK. Rock | K. Rock |
 John D'LeoVinny | Vinny |
 Stella MaeveCynthia | Cynthia |
 Raquel CastroKatherine | Katherine |
 Robert John BurkeState Trooper #1 | State Trooper #1 |
 Cle SloanNot listed | Not listed |
 Bruce MacVittieFather Scarpitta (as Bruce Macvittie) | Father Scarpitta (as Bruce Macvittie) |
 Sarah ThompsonSarie | Sarie |
 Thomas Jefferson ByrdUncle Jeb | Uncle Jeb |
 Lela RochonInvestigator #1 (as Lela Rochon Fuqua) | Investigator #1 (as Lela Rochon Fuqua) |
 Ed MoranInvestigator #2 | Investigator #2 |
 Isiah Whitlock Jr.Investigator #3 (as Isiah Whitlock) | Investigator #3 (as Isiah Whitlock) |
 Tawny CypressAllisa | Allisa |
