Madea winds up in the middle of mayhem when she spends a hilarious, haunted Halloween fending off killers, paranormal poltergeists, ghosts, ghouls, and zombies while keeping a watchful eye on a group of misbehaving teens.
| Actor | Role |
|---|---|
 Tyler PerryMabel "Madea" Simmons / Uncle Joe Simmons / Brian Simmons | Mabel "Madea" Simmons / Uncle Joe Simmons / Brian Simmons |
 Cassi DavisBetty Ann "Aunt Bam" Murphy | Betty Ann "Aunt Bam" Murphy |
 Diamond WhiteTiffany Simmons | Tiffany Simmons |
 Yousef ErakatJonathan | Jonathan |
 Bella ThorneRain Mathison | Rain Mathison |
 Liza KoshyAday Walker | Aday Walker |
 Patrice LovelyHattie Mae Love | Hattie Mae Love |
 Lexy PanterraLeah Devereaux | Leah Devereaux |
 Andre HallQuinton | Quinton |
| BBrock O'HurnHorse | Horse |
 Kian LawleyBean Boy | Bean Boy |
 Jimmy TatroSean | Sean |
 J.C. CaylenMikey | Mikey |
 Mike TornabeneDino | Dino |
 Abraham ClinkscalesKid 2 | Kid 2 |
 Jason VailPolice Officer #1 | Police Officer #1 |
| BBradley MartynFrat Guy #9 | Frat Guy #9 |
 TygaHimself | Himself |
 Andrew RushPolice Officer #2 | Police Officer #2 |
| TTyler ColeOfficer (uncredited) | Officer (uncredited) |