In this sequel, Bloodsucka Jones and his friends must battle zombies, weight gain, and tumbleweeds as they attempt to save the world from certain doom.
| Actor | Role |
|---|---|
| MMaria CanapinoVanessa | Vanessa |
| JJessica DercksChristine | Christine |
| JJustin ArmaoDavid | David |
 Matt KellyStewart | Stewart |
 Erin HoltHeather | Heather |
| BBrian GirardTimmy | Timmy |
| WWilliam CuttingKenny | Kenny |
 Jennifer RunyonNurse Zarkov | Nurse Zarkov |
 Nalini KrishanElvira | Elvira |
| AAndy CaubleKyle | Kyle |
 Nick PrincipeJay | Jay |
| AAlain AzoulayTodd Pepperjack | Todd Pepperjack |
 Chelsea CookJosie Death | Josie Death |
| EEvan mackRomeo Tyrone | Romeo Tyrone |
| SSean SummersFoltron | Foltron |
| LLauren Athena BirdsongBecky | Becky |
 Mindy RobinsonHanna Black | Hanna Black |
| PPreston GantBloodsucka Jones | Bloodsucka Jones |