The story of the Schaffer family, made up of terminally ill father Jack and his two daughters, bipolar Pappy, and Susannah, who tries to keep the family together despite it taking a strain on her romantic life.
| Actor | Role |
|---|---|
 Seymour CasselJack 'Pappy' Schaffer | Jack 'Pappy' Schaffer |
 Elisabeth MossPaulie Schaffer | Paulie Schaffer |
 Michael EsperJoey | Joey |
 Glenn FitzgeraldMoishe | Moishe |
| JJennifer AlbanoSusannah Schaffer | Susannah Schaffer |
 J. Smith-CameronViolet | Violet |
 Michael ZegenTodd | Todd |
 Matthew ArkinRabbi Rick | Rabbi Rick |
 Freddie RomanMartin | Martin |
 Irma St. PauleMrs. Windrowski | Mrs. Windrowski |
 John TormeyMurray | Murray |