Something is causing the rattlesnakes in Southern California to mutate to enormous sizes, and it’s up to Dr. Kaye to stop their growth before they destroy Los Angeles.
| Actor | Role |
|---|---|
 Brinke StevensRebecca | Rebecca |
 Mel NovakCommissioner Lewis | Commissioner Lewis |
 Shawn C. PhillipsTom / Son | Tom / Son |
 Dawna Lee HeisingLindsay / Mom | Lindsay / Mom |
 Julie Anne PrescottJessica | Jessica |
 Peter SticklesDeputy Morris | Deputy Morris |
 Jennifer NangleSally | Sally |
 Erik Anthony RussoDeputy Warrick | Deputy Warrick |
| JJoshua MoomeyAdam | Adam |
| EEric LarsenBig Mike | Big Mike |
| AAllie PerezAlly | Ally |
| JJarad AllenSally's Date | Sally's Date |
| HHunter BickhamJack | Jack |
 Mercedes PetersonDr. Kaye | Dr. Kaye |
| AAshley Morgan KilbrideJennifer | Jennifer |
 Scott ButlerProfessor McCauley | Professor McCauley |
| TThom Michael MulliganBridger | Bridger |
| DDawn DuVurgerDawn | Dawn |
| RRonnie AngelBlake | Blake |
 Ken MayMitch | Mitch |
| MMarvin 'Knife' SoteloMarcus | Marcus |
| DDustin WonchJason | Jason |
| TTino R. ZamoraStoner | Stoner |
| TTatiana LarreaMelissa | Melissa |
 Geovonna CasanovaSam | Sam |
| PPat KusnadiPete | Pete |
| DD.T. CarneySheriff Wilson | Sheriff Wilson |
 Dustin FergusonJeff | Jeff |