Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West's limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West's experiments 13 years earlier.
| Actor | Role |
|---|---|
 Jeffrey CombsDr. Herbert West | Dr. Herbert West |
 Jason BarryDr. Howard Phillips | Dr. Howard Phillips |
 Elsa PatakyLaura Olney | Laura Olney |
 Enrique ArceCabrera | Cabrera |
| NNico BaixasMoses | Moses |
 Lolo HerreroSergeant Moncho | Sergeant Moncho |
 Raquel GriblerVanessa | Vanessa |
 Simón AndreuBrando | Brando |
 Santiago SeguraSpeedball | Speedball |
| TTommy Dean MussetYoung Howard 'Howie' Phillips | Young Howard 'Howie' Phillips |
| BBárbara ElorrietaEmily Phillips | Emily Phillips |
 Joaquín OrtegaFalcon | Falcon |
 Daniel OrtizWinni | Winni |
| ÁÁngel PlanaKitchen Zombie | Kitchen Zombie |
| JJavier SandovalCop #1 | Cop #1 |
| CCésar NebredaBig Dude | Big Dude |
 Ignasi VidalS.W.A.T. Officer #1 | S.W.A.T. Officer #1 |
| MMiquel Àngel RipeuS.W.A.T. Officer #2 | S.W.A.T. Officer #2 |
| AAdan RodriguezS.W.A.T. Officer #3 | S.W.A.T. Officer #3 |