 Kevin BaconRobert Sherrod | Robert Sherrod |
 Corbin BleuEddie W. Robinson / Sgt. Dan Levin | Eddie W. Robinson / Sgt. Dan Levin |
 Patricia ClarksonMarguerite Higgins | Marguerite Higgins |
 Kevin ConnollyDonald Sanborn / Pvt. Raymond Howell | Donald Sanborn / Pvt. Raymond Howell |
 James CromwellMajor General Alexander A. Vandegrift / Fleet Admiral William Halsey | Major General Alexander A. Vandegrift / Fleet Admiral William Halsey |
 Blythe DannerElsa Maxwell | Elsa Maxwell |
 Viola DavisHortense Johnson | Hortense Johnson |
 Jesse EisenbergLt. Fiske Hanley / Sgt. Benjamin McKinney | Lt. Fiske Hanley / Sgt. Benjamin McKinney |
 John GoodmanCapt. Edwin Simmons | Capt. Edwin Simmons |
 Tom HanksNarrator | Narrator |
 Neil Patrick Harris1st Lt. David Hettema / Sgt. William Manchester | 1st Lt. David Hettema / Sgt. William Manchester |
 Kevin JonasMike Mervosh | Mike Mervosh |
 Tom KaneEdward R. Murrow | Edward R. Murrow |
 Justin LongCorp. James R. Garrett / Sgt. John H. Morris | Corp. James R. Garrett / Sgt. John H. Morris |
 Tobey MaguirePvt. George Strang | Pvt. George Strang |
 Joseph MazzelloEugene B. Sledge | Eugene B. Sledge |
 Daran Norris1940s Newscaster | 1940s Newscaster |
 Wendell PierceSgt. Thomas McPhatter | Sgt. Thomas McPhatter |
 Chris PineHanson Baldwin / Sgt. Bill Reed | Hanson Baldwin / Sgt. Bill Reed |
 Brad PittSgt. Bill Mauldin | Sgt. Bill Mauldin |
 William SadlerLt. Colonel Lewis B. 'Chesty' Puller | Lt. Colonel Lewis B. 'Chesty' Puller |
 Gary SiniseErnie Pyle | Ernie Pyle |
 Elijah WoodCorp. Wilfred Hanson / Capt. John C. Chapin | Corp. Wilfred Hanson / Capt. John C. Chapin |
