The true story of two murders that shaped the lives of several college students who went on to become some of the most influential writers of the "Beat Generation."
| Actor | Role |
|---|---|
 Kiefer SutherlandWilliam S. Burroughs | William S. Burroughs |
 Courtney LoveJoan Vollmer Burroughs | Joan Vollmer Burroughs |
 Ron LivingstonAllen Ginsberg | Allen Ginsberg |
 Norman ReedusLucien Carr | Lucien Carr |
 Sam TrammellLee | Lee |
| AAlec Von BargenHeard | Heard |
| TTommy PernaDwight | Dwight |
 Daniel MartínezJack Kerouac | Jack Kerouac |
 Kyle SecorDave Kammerer | Dave Kammerer |
 Luisa HuertasMaria (uncredited) | Maria (uncredited) |
 Lisa SheridanSadie | Sadie |