The story of four lifelong friends who met in the 2000s when they were presidents of the BDE of the Nantes Institute of Business. At the time, they were the "Bioman": the kings of partying, excess and "transmutation". 20 years later, they have mellowed out and lead well-ordered lives. Except... Once a year, when they get together for the WEB: the Bioman Weekend. There, they "transmute" hard as they like to say. In short: they drink and sing in a pathetic way.
| Actor | Role |
|---|---|
 Michaël YounBob | Bob |
 Héléna NoguerraRomane | Romane |
 Lucien Jean-BaptisteMax | Max |
 Vincent DesagnatVinz | Vinz |
 Rayane BensettiSamy | Samy |
 LudovikPablo | Pablo |
 Manon AzemBarbara | Barbara |
 Virginie HocqMarielle Pichu | Marielle Pichu |
 Gilbert MelkiIlan Cohen | Ilan Cohen |
 Tomer SisleyDany Frydman | Dany Frydman |
 Michèle LaroqueHannah Cohen | Hannah Cohen |
 Judith El ZeinMorgane | Morgane |
 Benjamin MorgaineBenyamin | Benyamin |
 Sébastien ChabalMouche, l'ogre | Mouche, l'ogre |
 Rébecca BenhamourCowgirl | Cowgirl |
 Miglen MirtchevKapitan | Kapitan |
 Lola DubiniJess | Jess |
| EElodie BarthelsOffice worker (uncredited) | Office worker (uncredited) |
 Jérôme Le BannerTiti, la brute | Titi, la brute |
 Pierre LottinJason, l'excité | Jason, l'excité |
 Michaël AbiteboulMichel le policier | Michel le policier |
 Jean-Luc CouchardDjo, le patriarche | Djo, le patriarche |
 Jimmy LabeeuFil | Fil |
 CartmanIgor | Igor |
 Wahid BouzidiCodétenu cellule | Codétenu cellule |