Santo goes up against the vampire Baron Brakola, who has returned to seek vengeance on the descendants of the Knight in the Silver Mask (Santo's colonial era ancestor).
| Actor | Role |
|---|---|
 El SantoSanto | Santo |
 Fernando OsésBaron Brákola | Baron Brákola |
 Mercedes CarreñoSilvia (as Mercedes Carreño) | Silvia (as Mercedes Carreño) |
| AAntonio de HudEduardo | Eduardo |
 Andrea PalmaRebeca's Mother | Rebeca's Mother |
 Ada CarrascoAurora | Aurora |
| SSusana RoblesRebeca | Rebeca |
| QQuasimodoLuchador | Luchador |