When the strain of tragedy was too much for a young couple in Appalachia, prescription pills became the medicine to ease the pain.
| Actor | Role |
|---|---|
 A.J. CookNida | Nida |
 Josh StewartWaylon | Waylon |
 Agnes BrucknerRaylene | Raylene |
 Wade WilliamsCotton | Cotton |
 Dorothy LymanSusie | Susie |
 David SelbyBill | Bill |
 Eden BrolinNona | Nona |
 Ronnie Gene BlevinsJimmy | Jimmy |
 Rebecca GrussAnne | Anne |
 Sloane CoombsJustine | Justine |
| TTravis TeffnerDude | Dude |
| JJeremy Michael BurnsMan #2 | Man #2 |
| CCathy O'DellJanet | Janet |
| PPhillip RushEnoch | Enoch |
| GGant MontgomeryCharlie | Charlie |
| LLindsey SitesBrunette in Bar | Brunette in Bar |
 Kevin DennisBackground | Background |
| MMadeline GehleGirl in Bar | Girl in Bar |
| PPorter StilesMan #1 | Man #1 |
 Mandy SimpsonBlonde Silhouette | Blonde Silhouette |