A veteran-turned-mercenary is hired to take a young woman with a secret from post-apocalyptic Eastern Europe to New York City.
| Actor | Role |
|---|---|
 Vin DieselToorop | Toorop |
 Mélanie ThierryAurora | Aurora |
 Lambert WilsonDr. Arthur Darquandier | Dr. Arthur Darquandier |
 Charlotte RamplingCEO of Noelite Church | CEO of Noelite Church |
 Michelle YeohSister Rebeka | Sister Rebeka |
 Gérard DepardieuGorsky | Gorsky |
 Mark StrongFinn | Finn |
 Jérôme Le BannerKilla | Killa |
 David BelleHacker Kid | Hacker Kid |
 Joel KirbyDr. Newton | Dr. Newton |
 Radek BrunaKarl | Karl |
 Jan UngerFight Promoter | Fight Promoter |
 Abraham BelagaAssistant to High Priestess | Assistant to High Priestess |
 David GasmanNeolite Researcher | Neolite Researcher |
| GGary CowanNeolite Executive | Neolite Executive |
 Lemmy ConstantineNeolite Marketing Executive | Neolite Marketing Executive |
 Pete ThiasNeolite MIB | Neolite MIB |
 Curtis MatthewSubmarine Captain | Submarine Captain |
 SoloJamal | Jamal |
| AAlex Vladimír PieterS.W.A.T. Soldier | S.W.A.T. Soldier |
| RRobert PoloBorder Guard | Border Guard |