‘Awe’ charts the journey of a motley of characters that have nothing to do with each other but are yet connected by a single, fragile string. Who are these people and what about their lives connect them to each other is what the film is all about.
| Actor | Role |
|---|---|
 Kajal AggarwalKali | Kali |
 Eesha RebbaRadha | Radha |
 Nithya MenenKrishnaveni | Krishnaveni |
 Regena CassandrraMeera | Meera |
 Priyadarshi PullikondaNala | Nala |
 Srinivas AvasaralaShiva | Shiva |
 Murali SharmaYogi | Yogi |
| KKaitelyn "Kate D'melloMoksha | Moksha |
 RohiniRadha’s Mother | Radha’s Mother |
 C. V. L. Narasimha RaoRadha's Father | Radha's Father |
 DevadarshiniParvathy | Parvathy |
 Pragathi MahavadiChitra | Chitra |
 Jayasri RachakondaDevi | Devi |
| UUpen ReddyLobo / Sugar | Lobo / Sugar |
 NaniHumanitarian Fish "Nani" (Voice) | Humanitarian Fish "Nani" (Voice) |
 Ravi TejaBonsai Tree "Chanti" (Voice) | Bonsai Tree "Chanti" (Voice) |