Emily Johnson, her boyfriend Bobby and their friends Clare and Jude are recent college grads driving cross-country, taking a last vacation together before they face the "real" world. An accident leaves them hurt and stranded on a lonely Louisiana road. When the ambulance arrives, it whisks them to Mercy Hospital.
| Actor | Role |
|---|---|
 Robert PatrickDr. David Benway | Dr. David Benway |
 Jessica LowndesEmily | Emily |
 Jenette GoldsteinNurse Marian | Nurse Marian |
 Michael BowenTravis | Travis |
 Robert LaSardoScott | Scott |
 Ross KohnBobby | Bobby |
 Ashley SchneiderClare | Clare |
 Ross McCallJude | Jude |
| AArcadiy GolubovichDmitriy | Dmitriy |
 Gregg BrazzelMan Under Car | Man Under Car |
| EElijah HardyGregory | Gregory |
| TTatyana KanavkaGretchen | Gretchen |
| JJanine VenableLisette | Lisette |
| KKevin M. WhiteMan in Hall | Man in Hall |
| JJeff L. DeistScarred Naked Man | Scarred Naked Man |
| EEric F. AdamsOfficer Jacobs | Officer Jacobs |