Atrabilious follows Steven Joyner as he tries to solve the mystery behind his son's sudden, tragic and potentially fabricated death. He is led to the titular bar, Atrabilious, and begins to unravel the history of the establishment.
| Actor | Role |
|---|---|
 Leon Addison BrownSteven Joyner | Steven Joyner |
 Mark Boone JuniorDr. Eduard Gillespie | Dr. Eduard Gillespie |
 Evan JonigkeitDr. Raphael Clearwater | Dr. Raphael Clearwater |
 Jeffrey WrightVincent Daugherty | Vincent Daugherty |
 Whoopi GoldbergDr. Andrea Hart | Dr. Andrea Hart |
 Brooks AshmanskasTodd Jenkins | Todd Jenkins |
 Lewis BlackRoy Altman | Roy Altman |
 Joel de la FuenteMark Nava | Mark Nava |
 Hunter ParrishMilo Kramer | Milo Kramer |
 Alec BaldwinProctor Carlisle | Proctor Carlisle |
 Will Atticus ParkerAnton Kantoliev | Anton Kantoliev |
 Steven MaierBradley Atkinson | Bradley Atkinson |
 David PittuDomonick Calderon | Domonick Calderon |
 Andy KarlGreg Meyers | Greg Meyers |
 Ward HortonMiles Zimmerman | Miles Zimmerman |
 Michelangelo MilanoFrank Webster | Frank Webster |
 Jaden MichaelGregori Kantoliev | Gregori Kantoliev |
 Sabina Friedman-SeitzKate Sullivan | Kate Sullivan |
 Dan FinnertyLevi Walker | Levi Walker |
 Will HochmanCharles | Charles |
| AAdam PiacenteAlan Kantoliev | Alan Kantoliev |