 Mark RendallArthur Read (voice) | Arthur Read (voice) |
 Jodie RestherFrancine Frensky (voice) | Francine Frensky (voice) |
 Melissa AltroMuffy Crosswire (voice) | Muffy Crosswire (voice) |
 Bruce DinsmoreDavid Read / Binky Barnes (voice) | David Read / Binky Barnes (voice) |
 Holly Gauthier-FrankelFern Walters (voice) | Fern Walters (voice) |
 Maggie CastleMolly MacDonald (voice) | Molly MacDonald (voice) |
 Bronwen MantelMrs. MacGrady (voice) | Mrs. MacGrady (voice) |
 Nick CarterSelf - Backstreet Boys (voice) | Self - Backstreet Boys (voice) |
 Howie DoroughSelf - Backstreet Boys (voice) | Self - Backstreet Boys (voice) |
 Brian LittrellSelf - Backstreet Boys (voice) | Self - Backstreet Boys (voice) |
 Kevin RichardsonSelf - Backstreet Boys (voice) | Self - Backstreet Boys (voice) |
 AJ McLeanSelf - Backstreet Boys (voice) | Self - Backstreet Boys (voice) |
| JJason SzwimmerDora Winifred 'D.W.' Read (voice) | Dora Winifred 'D.W.' Read (voice) |
 Daniel BrochuBuster Baxter (voice) | Buster Baxter (voice) |
 Sonja BallJane Read (voice) | Jane Read (voice) |
 Tracy BraunsteinKate Read (voice) | Kate Read (voice) |
 Ellen DavidBitzi Baxter (voice) | Bitzi Baxter (voice) |
| AA.J. HendersonEd Crosswire (voice) | Ed Crosswire (voice) |
 Arthur HoldenMr. Ratburn (voice) | Mr. Ratburn (voice) |
 Jonathan KoensgenTommy Tibble (voice) | Tommy Tibble (voice) |
| SSamuel HoldenTimmy Tibble (voice) | Timmy Tibble (voice) |
 Alex HoodAlan 'The Brain' Powers (voice) | Alan 'The Brain' Powers (voice) |
| KKate HutchisonPaige Turner (voice) | Paige Turner (voice) |
| TTamar KozlovPrunella Deegan (voice) | Prunella Deegan (voice) |
 Greg KramerNemo (voice) | Nemo (voice) |
 Vanessa LengiesEmily (voice) | Emily (voice) |
 Walter MasseyPrincipal Haney (voice) | Principal Haney (voice) |
| JJoanna NoyesGrandma Thora Read (voice) | Grandma Thora Read (voice) |
 Simon PeacockPal (voice) | Pal (voice) |
| HHayley ReynoldsNadine (voice) | Nadine (voice) |
