Plain Jane Hartman hates her life. She's goofy, boring and only has sex if she reads Iris Murdoch novels out loud to her loopy boyfriend. Her oldest friend Antonia McGill knows about everything. She orders the right food; she can complain and get results. She's beautiful and has a brilliant career. Is it any wonder that they hate each other's guts?
| Actor | Role |
|---|---|
 Imelda StauntonJane Hartman | Jane Hartman |
 Saskia ReevesAntonia McGill | Antonia McGill |
 Bill NighyHoward Nash | Howard Nash |
 Brenda BruceTherapist | Therapist |
 Richard HopeNorman Beer | Norman Beer |
 Lila KayeJane's Mother | Jane's Mother |
 Alfred MarksUncle Vladimir Hartman | Uncle Vladimir Hartman |
 Joe AbsolomDaniel Nash | Daniel Nash |
 Allan CordunerStephen Carlinsky | Stephen Carlinsky |
 Ian RedfordJeremy Woodward | Jeremy Woodward |
 John BennettUncle Irwin Carlinsky | Uncle Irwin Carlinsky |
 Maria CharlesSylvia Pinker | Sylvia Pinker |
| PPatricia LeventonRosa Gluberman | Rosa Gluberman |
| AAlfred HoffmanHarry Rosenthal | Harry Rosenthal |
 Iain CuthbertsonEdgar | Edgar |
| SSheila AllenTutor | Tutor |
 Trevor PeacockA.D. Humphries | A.D. Humphries |
 Peter WingfieldTaxi Driver | Taxi Driver |
| BBonnie ParkerYoung Jane | Young Jane |
| TTania RodriguesPolicewoman | Policewoman |
| CClaire RaynerHerself | Herself |
 Michael IgnatieffHimself | Himself |