Young Phoebe Mosey (Jamie Lee Curtis) defies expectations and proves herself to become "Little Miss Sure Shot" Annie Oakley, the legendary sharpshooter and "Wild West" icon.
| Actor | Role |
|---|---|
 Jamie Lee CurtisAnnie Oakley | Annie Oakley |
 Brian DennehyBuffalo Bill | Buffalo Bill |
 Cliff DeYoungFrank Butler | Frank Butler |
 Nancy LenehanLyda | Lyda |
 Lu LeonardQueen Victoria | Queen Victoria |
 Joyce Van PattenMa | Ma |
 Shelley DuvallThe Host | The Host |
 Donovan ScottJoe | Joe |
 David McCharenCowboy Pete | Cowboy Pete |
 ApesanahkwatInterpreter | Interpreter |
 Anne Marie McEvoyYoung Annie | Young Annie |
| NNick RamusSitting Bull | Sitting Bull |
| JJohn AchornThomas Edison | Thomas Edison |
| DDouglas MilbrandSmall Boy | Small Boy |
| BBill TurnerReporter | Reporter |
| JJ. David WayneCowboy | Cowboy |