 Tom HanksRobert Langdon | Robert Langdon |
 Ewan McGregorCamerlengo Patrick McKenna | Camerlengo Patrick McKenna |
 Ayelet ZurerVittoria Vetra | Vittoria Vetra |
 Stellan SkarsgårdCommander Richter | Commander Richter |
 Pierfrancesco FavinoInspector Olivetti | Inspector Olivetti |
 Nikolaj Lie KaasAssassin | Assassin |
 Armin Mueller-StahlCardinal Strauss | Cardinal Strauss |
 Thure LindhardtChartrand | Chartrand |
 David PasquesiClaudio Vincenzi | Claudio Vincenzi |
 Cosimo FuscoFather Simeon | Father Simeon |
 Victor AlfieriLieutenant Valenti | Lieutenant Valenti |
| FFranklin AmobiCardinal Lamasse | Cardinal Lamasse |
 Curt LowensCardinal Ebner | Cardinal Ebner |
 Bob YerkesCardinal Guidera | Cardinal Guidera |
 Marc FioriniCardinal Baggia | Cardinal Baggia |
 Carmen ArgenzianoFather Silvano Bentivoglio | Father Silvano Bentivoglio |
 Howard MungoCardinal Yoruba | Cardinal Yoruba |
 Rance HowardCardinal Beck | Cardinal Beck |
 Steve FrankenCardinal Colbert | Cardinal Colbert |
 Gino ConfortiCardinal Pugini | Cardinal Pugini |
 Elya BaskinCardinal Petrov | Cardinal Petrov |
| RRichard RosettiConclave Cardinal | Conclave Cardinal |
| SSilvano MarchettoConclave Cardinal | Conclave Cardinal |
 Thomas MorrisUrs Weber | Urs Weber |
 Jonas FischAdrian Bachman | Adrian Bachman |
 August WittgensteinSwiss Guardsman | Swiss Guardsman |
 Ben Bela BöhmSwiss Guardsman | Swiss Guardsman |
| PPaul SchmitzSwiss Guardsman | Swiss Guardsman |
 Jeffrey BoehmSwiss Guard Blue | Swiss Guard Blue |
| XXavier J. NathanPhilippe | Philippe |
