A genetically created Anaconda, cut in half, regenerates itself into two new aggressive giant snakes, due to the Blood Orchid.
| Actor | Role |
|---|---|
 Crystal AllenDr. Amanda Hayes | Dr. Amanda Hayes |
 Linden AshbyJackson | Jackson |
 Danny MidwinterScott | Scott |
 Calin StanciuAlex | Alex |
 John Rhys-DaviesPeter "J.D." Murdoch | Peter "J.D." Murdoch |
 Ana UlaruHeather | Heather |
 Claudiu BleonţArmon | Armon |
 Anca AndroneWendy | Wendy |
 Emil HostinaEugene | Eugene |
 Alexandru PotoceanRoland / Patrick | Roland / Patrick |
 Dan BadarauVasile | Vasile |
 Marcel CobzariuMercenary #1 | Mercenary #1 |
 Elias FerkinMercenary #2 | Mercenary #2 |
| RRazvan GheorghiuMercenary #3 | Mercenary #3 |
| VVasile AlbinețMercenary #4 | Mercenary #4 |
| ZZoltan ButucPeter | Peter |
| CCristina TeodorescuMurdoch's Assistant | Murdoch's Assistant |