Jackson is back, and now he has a new partner, karate champion Sean, as they must face a deadly terrorist known as "The Cobra", who has infected Sean with a virus. Sean and Jackson have no choice but to fight the Cobra and his bands of ninjas.
| Actor | Role |
|---|---|
 David BradleySean Davidson | Sean Davidson |
 Steve JamesCurtis Jackson | Curtis Jackson |
 Marjoe GortnerThe Cobra | The Cobra |
 Michele B. ChanChan Lee | Chan Lee |
 Yehuda EfroniGeneral Andreas | General Andreas |
 Calvin JungIzumo | Izumo |
 Adrienne PearceMinister's Secretary | Minister's Secretary |
| EEvan J. KlisserDexter | Dexter |
| GGrant PrestonMinister of Interior | Minister of Interior |
 Michael HuffDr. Holger | Dr. Holger |
| AAlan SwerdlowPolice Captain | Police Captain |
| TThapelo MofokengPolice Sergeant | Police Sergeant |
| EEkard RabiSean's Father | Sean's Father |
| SStephen WebberYoung Sean | Young Sean |
| JJerry TsieMartial Artist | Martial Artist |
 Mike StoneTournament Arbiter (uncredited) | Tournament Arbiter (uncredited) |